Structure of PDB 8gah Chain B

Receptor sequence
>8gahB (length=432) Species: 562 (Escherichia coli) [Search protein sequence]
KTPLAILFMAAVVGTLVGLAAVAFDKGVAWLQNQRMGALVHTADNYPLLL
TVAFLASAVLAMFGYFLVRKYAPEAGGSGIPEIEGALEDQRPVRWWRVLP
VKFFGGLGTLGGGMVLGREGPTVQIGGNIGRMVLDIFRLKGDEARHTLLA
TGAAAGLAAAFNAPLAGILFIIEEMRPQFRYTLISIKAVFIGVIMSTIMY
RIFNHEVALIDVGKLSDAPLNTLWLYLILGIIFGIFGPIFNKWVLGMQDL
LHRVHGGNITKWVLMGGAIGGLCGLLGFVAPATSGGGFNLIPIATAGNFS
MGMLVFIFVARVITTLLCFSSGAPGGIFAPMLALGTVLGTAFGMVAVELF
PQYHLEAGTFAIAGMGALLAASIRAPLTGIILVLEMTDNYQLILPMIITG
LGATLLAQFTGGKPLYSAILCRTLAKQEAEQL
3D structure
PDB8gah Structural basis of pH-dependent activation in a CLC transporter.
ChainB
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CL B S107 G355 Y445 S78 G326 Y416
Gene Ontology
Molecular Function
GO:0005247 voltage-gated chloride channel activity
GO:0015297 antiporter activity
GO:0042802 identical protein binding
GO:0062158 chloride:proton antiporter activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0006821 chloride transport
GO:0055085 transmembrane transport
GO:1902476 chloride transmembrane transport
GO:1902600 proton transmembrane transport
GO:1990451 cellular stress response to acidic pH
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8gah, PDBe:8gah, PDBj:8gah
PDBsum8gah
PubMed38279055
UniProtP37019|CLCA_ECOLI H(+)/Cl(-) exchange transporter ClcA (Gene Name=clcA)

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