Structure of PDB 8g8v Chain B

Receptor sequence
>8g8vB (length=254) Species: 28450 (Burkholderia pseudomallei) [Search protein sequence]
QSTVDTRQMPIQRVGVRAVRHPLTVRTAEGETQATVGTWNLDVHLPADQK
GTHMSRFVALLEERGGPLTADAFRTMLATMLEKLEARAGRIEVSFPYFVN
KTAPVSGVRSLLDYEVTLTGDVRDGLTRVFAKVLVPVTSLCPCSKKISQY
GAHNQRSHVTIDAELAADVPVEDLIRIAEEEASCELWGLLKRPDEKFVTE
RAYENPKFVEDLVRDVARRLDADERIVAYVLEAENFESIHNHSAYALIER
DKRR
3D structure
PDB8g8v Combatting melioidosis with chemical synthetic lethality
ChainB
Resolution2.03 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.5.4.16: GTP cyclohydrolase I.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SO3 B F221 E223 F208 E210
BS02 SO3 B P109 E128 P96 E115
BS03 SO3 B T132 D175 T119 D162
Gene Ontology
Molecular Function
GO:0003933 GTP cyclohydrolase activity
GO:0003934 GTP cyclohydrolase I activity
GO:0016787 hydrolase activity
Biological Process
GO:0046654 tetrahydrofolate biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:8g8v, PDBe:8g8v, PDBj:8g8v
PDBsum8g8v
PubMed
UniProtQ63JF5|GCH4_BURPS GTP cyclohydrolase FolE2 (Gene Name=folE2)

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