Structure of PDB 8g5f Chain B

Receptor sequence
>8g5fB (length=331) Species: 10090 (Mus musculus) [Search protein sequence]
NMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDY
TLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVH
GVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESY
GYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVVFSTGSYPR
LSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITT
VLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFMALLEYALVNYIFF
GTDVNAIDRWSRIFFPVVFSFFNIVYWLYYV
3D structure
PDB8g5f Cryo-EM structures reveal native GABA A receptor assemblies and pharmacology.
ChainB
Resolution2.64 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ABU B Y157 T202 Y205 Y150 T195 Y198
BS02 Y4B B A300 L301 Y304 A293 L294 Y297
Gene Ontology
Molecular Function
GO:0004888 transmembrane signaling receptor activity
GO:0004890 GABA-A receptor activity
GO:0005216 monoatomic ion channel activity
GO:0005230 extracellular ligand-gated monoatomic ion channel activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0034220 monoatomic ion transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8g5f, PDBe:8g5f, PDBj:8g5f
PDBsum8g5f
PubMed37730991
UniProtP63137|GBRB2_MOUSE Gamma-aminobutyric acid receptor subunit beta-2 (Gene Name=Gabrb2)

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