Structure of PDB 8fvs Chain B

Receptor sequence
>8fvsB (length=116) Species: 9606 (Homo sapiens) [Search protein sequence]
KKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKN
PMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKL
AEVFEQEIDPVMQSLG
3D structure
PDB8fvs Group 3 medulloblastoma transcriptional networks are sensitive to EP300/CBP bromodomain inhibition
ChainB
Resolution1.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.48: histone acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 YBE B P1110 Q1113 V1115 N1168 V1174 P29 Q32 V34 N87 V93
Gene Ontology
Molecular Function
GO:0004402 histone acetyltransferase activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:8fvs, PDBe:8fvs, PDBj:8fvs
PDBsum8fvs
PubMed38664416
UniProtI3L466

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