Structure of PDB 8foh Chain B

Receptor sequence
>8fohB (length=406) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
EEKKLYARLYESKLSFYDLPPQEQFEIWAIDRLKILLEIESCLSRNKSIK
EIETIIKPQFQKLLPFNTESLEDRKKDYYSHFILRLCFCRSKELREKFVR
AETFLFKIRFNMLTSTDQTKFVQSLQFISNEEKAELSHQLYQTVSASLQF
QLNLNEEHQRKQYFQQEKFIKLPFENVIELVGNRLVFLKDGYAYLQQLNL
LSNEFASKLNQELIKTYQYLPRLNEDRLLPILNHLSSGYTDEINAQSVWS
EEISSNYPLCIKNLMEGLKKNHHLRYYGRQQLSLFLKGIGLSADEALKFW
SEAFTKEYRYSFRHNYGLEGNRINYKPWDCHTILSKPRPGRGDYHGCPFR
DWSHERLSAELRAQIISVLDSCQKGEYTIACTKVFEMTHHIAHPNLYFER
SRQLQK
3D structure
PDB8foh Molecular choreography of primer synthesis by the eukaryotic Pol alpha-primase.
ChainB
Resolution4.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B K393 H401 N408 K306 H314 N321
BS02 SF4 B P334 C336 C417 I420 C434 F436 T471 C474 P500 P258 C260 C330 I333 C347 F349 T378 C381 P394
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003697 single-stranded DNA binding
GO:0003896 DNA primase activity
GO:0046872 metal ion binding
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication
GO:0006269 DNA replication, synthesis of primer
GO:0006270 DNA replication initiation
GO:0006302 double-strand break repair
Cellular Component
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005658 alpha DNA polymerase:primase complex
GO:1990077 primosome complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8foh, PDBe:8foh, PDBj:8foh
PDBsum8foh
PubMed37344454
UniProtP20457|PRI2_YEAST DNA primase large subunit (Gene Name=PRI2)

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