Structure of PDB 8fo5 Chain B

Receptor sequence

>8fo5B (length=215) Species: 9606 (Homo sapiens)

QSALTQPPSASGSPGQSVTISCTGTSSDVGGSDSVSWYQQHPGKAPKLII
YEVSQRPSGVPNRFSGSKSGNTASLTVSGLQAEDDADYYCSSYGGDNNLF
FGGGTKVTVLGQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTV
AWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVT
HEGSTVEKTVAPTEC

3D structure

• PDB: 8fo5 Crystal Structures of Diaryl Hydrazone and Sulfone Stabilizers in Complex with an Amyloidogenic Light Chain Reveal an Alternate Ligand-Binding Cavity
• Chain: B
• Resolution: 1.89 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	Y4U	B	Y38 P46	Y38 P46

External links

• PDB: RCSB:8fo5, PDBe:8fo5, PDBj:8fo5
• PDBsum: 8fo5