Structure of PDB 8fk4 Chain B

Receptor sequence
>8fk4B (length=821) Species: 1309 (Streptococcus mutans) [Search protein sequence]
KKQVYDRSAQSFEHVDHYLTAESWYRPDGKTWTQSTEKDFRPLLMTWWPS
QETQRQYVNYMNAQLGINKTYDDTSNQLQLNIAAATIQAKIEAKITTLKN
TDWLRQTISAFVKTQSAWNSDSEKPFDDHLQNGAVLYDNEGKLTPYANSN
YRILNRTPTNQTGKKDPRYTADNTIGGYEFLLANDVDNSNPVVQAEQLNW
LHFLMNFGNIYANDPDANFDSIRVDAVDNVDADLLQIAGDYLKAAKGIHK
NDKAANDHLSILEAWSDNDTPYLHDDGDNMINMDNKLRLSLLFSLAKPLN
QRSGMNPLITNSLVNRTDDNAETAAVPSYSFIRAHDSEVQDLIRDIIKAE
INPNVVGYSFTMEEIKKAFEIYNKDLLATEKKYTHYNTALSYALLLTNKS
SVPRVYYGDMFTDDGQYMAHKTINYEAIETLLKARIKYVSGGQAMRNQQV
GNSEIITSVRYGKGALKATDTGDRTTRTSGVAVIEGNNPSLRLKASDRVV
VNMGAAHKNQAYRPLLLTTDNGIKAYHSDQEAAGLVRYTNDRGELIFTAA
DIKGYANPQVSGYLGVWVPVGAAADQDVRVAASTAPSTDGKSVHQNAALD
SRVMFEGFSNFQAFATKKEEYTNVVIAKNVDKFAEWGVTDFEMAPQYVSS
TDGSFLDSVIQNGYAFTDRYDLGISKPNKYGTADDLVKAIKALHSKGIKV
MADWVPDQMYAFPEKEVVTATRVDKFGKPVEGSQIKSVLYVADSKSSGKD
QQAKYGGAFLEELQAKYPELFARKQISTGVPMDPSVKIKQWSAKYFNGTN
ILGRGAGYVLKDQATNTYFNI
3D structure
PDB8fk4 The catalytic domains of Streptococcus mutans glucosyltransferases: a structural analysis
ChainB
Resolution3.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.1.5: dextransucrase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GLC B Y404 W491 Y178 W265
BS02 AC1 B L407 D451 E489 W491 H561 D562 D883 Y890 Q934 L181 D225 E263 W265 H335 D336 D657 Y664 Q708
BS03 CA B E405 D411 N455 D933 E179 D185 N229 D707
Gene Ontology
Molecular Function
GO:0046527 glucosyltransferase activity
Biological Process
GO:0009250 glucan biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:8fk4, PDBe:8fk4, PDBj:8fk4
PDBsum8fk4
PubMed37158310
UniProtP08987|GTFB_STRMU Glucosyltransferase-I (Gene Name=gtfB)

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