Structure of PDB 8fji Chain B

Receptor sequence
>8fjiB (length=170) Species: 9606 (Homo sapiens) [Search protein sequence]
NSLALHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDG
EEVQIDILDTAGQEDYAAIRDNYFRSGEGFLCVFSITEMESFAATADFRE
QILRVKEDENVPFLLVGNKSDLEDKRQVSVEEAKNRAEQWNVNYVETSAK
TRANVDKVFFDLMREIRARL
3D structure
PDB8fji Exploring Covalent Bond Formation at Tyr-82 for Inhibition of Ral GTPase Activation.
ChainB
Resolution1.48 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.6.5.2: small monomeric GTPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GDP B G24 V25 G26 K27 S28 A29 F39 E41 N127 K128 D130 L131 S157 A158 G15 V16 G17 K18 S19 A20 F30 E32 N118 K119 D121 L122 S148 A149
BS02 Y0M B A48 T69 A70 G71 Q72 E73 R79 Y82 A39 T60 A61 G62 Q63 E64 R70 Y73
BS03 CA B L14 E87 L5 E78
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0007165 signal transduction
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8fji, PDBe:8fji, PDBj:8fji
PDBsum8fji
PubMed37269475
UniProtP11233|RALA_HUMAN Ras-related protein Ral-A (Gene Name=RALA)

[Back to BioLiP]