Structure of PDB 8fjh Chain B

Receptor sequence
>8fjhB (length=170) Species: 9606 (Homo sapiens) [Search protein sequence]
NSLALHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDG
EEVQIDILDTAGQEDYAAIRDNYFRSGEGFLCVFSITEMESFAATADFRE
QILRVKEDENVPFLLVGNKSDLEDKRQVSVEEAKNRAEQWNVNYVETSAK
TRANVDKVFFDLMREIRARL
3D structure
PDB8fjh Exploring Covalent Bond Formation at Tyr-82 for Inhibition of Ral GTPase Activation.
ChainB
Resolution1.54 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.2: small monomeric GTPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GDP B G24 V25 G26 K27 S28 A29 F39 E41 N127 K128 D130 L131 S157 A158 K159 G15 V16 G17 K18 S19 A20 F30 E32 N118 K119 D121 L122 S148 A149 K150
BS02 Y0P B A48 T69 A70 G71 Q72 E73 R79 Y82 F83 A39 T60 A61 G62 Q63 E64 R70 Y73 F74
BS03 CA B L14 E87 L5 E78
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0007165 signal transduction
Cellular Component
GO:0016020 membrane

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Cellular Component
External links
PDB RCSB:8fjh, PDBe:8fjh, PDBj:8fjh
PDBsum8fjh
PubMed37269475
UniProtP11233|RALA_HUMAN Ras-related protein Ral-A (Gene Name=RALA)

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