Structure of PDB 8ffz Chain B

Receptor sequence
>8ffzB (length=905) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
MVLTIYPDELVQIVSDKIASNKGKITLNQLWDISGKYFDLSDKKVKQFVL
SCVILKKDIEVYCDGAITTKNVTDIIGDANHSYSVGITEDSLWTLLTGYT
KKESTIGNSAFELLLEVAKSGEKGINTMDLAQVTGQDPRSVTGRIKKINH
LLTSSQLIYKGHVVKQLKLKKFINIRDHLATIVEVVKRSKNGIRQIIDLK
RELKFDKEKRLSKAFIAAIAWLDEKEYLKKVLVVSPKNPAIKIRCVKYVK
DIPDNFNATDLLQNQGLVMEEKEVLLNRFYPLQNQTYDIADKSGLKGIST
MDVVNRITGKEFQRAFTKSSEYYLESVGYRLFRIYDFEGKKKFFRLFTAQ
NFQKLTNPKGFDELGKSRTDLKTLNEDNFVALNNTVRFTTDSDGQDIFFW
HGERSLRSLQRQRAILKVMNTIGGVAYLREQFYESVSKYMGSTTTLDKKT
VRGDVDLMVESEKLGARTEPVSGRKIIFLPTVGEDAIQRYILKEKDSKKA
TFTDVIHDTEIYFKDGVQALIRAVVVTKSIKNEIMWDKITKLFPNNSLDN
LKKKWTARRVRMGHSGWRAYVDKWKKMLVLAIKSEKISLRDVEELDLIKL
LDIWTSFDEKEIKRPLFLYKNYEENRKKFTLVRDMSSMIQREISSLKKTY
TRKISASTKDLSKSQSDDYIRTVIRSILIESNEIEALKNVGNESIDNVIM
DMAKEKQIYLHGSKLECTDTLPDILENRGNYKDFGVAFQYRCKVNELLEA
GNAIVINQEPSDISSWVLIDLISGELLNMDVIPMVEIRTLTPPLIIYANS
QTKLNTARKSAVKVPLGKPFSRLWVNGSGSIRPNIWKQVVTMVVNEIIFH
PGITLSRLQSRCREVLSLHEISEICKWLLERQVLITTDFDGYWVNHNWYS
IYEST
3D structure
PDB8ffz Structural basis of TFIIIC-dependent RNA polymerase III transcription initiation.
ChainB
Resolution3.8 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B R144 K147 Y395 F404 R1063 R144 K147 Y335 F344 R808
BS02 dna B K146 N450 N451 K146 N383 N384
Gene Ontology
Molecular Function
GO:0001002 RNA polymerase III type 1 promoter sequence-specific DNA binding
GO:0001003 RNA polymerase III type 2 promoter sequence-specific DNA binding
GO:0003677 DNA binding
GO:0008301 DNA binding, bending
Biological Process
GO:0006383 transcription by RNA polymerase III
GO:0006384 transcription initiation at RNA polymerase III promoter
GO:0042791 5S class rRNA transcription by RNA polymerase III
GO:0071168 protein localization to chromatin
Cellular Component
GO:0000127 transcription factor TFIIIC complex
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005739 mitochondrion

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8ffz, PDBe:8ffz, PDBj:8ffz
PDBsum8ffz
PubMed37402369
UniProtP34111|TFC3_YEAST Transcription factor tau 138 kDa subunit (Gene Name=TFC3)

[Back to BioLiP]