Structure of PDB 8fbl Chain B

Receptor sequence
>8fblB (length=278) Species: 9606 (Homo sapiens) [Search protein sequence]
LKNVFSVLLIFIYLLLMAVAVFLVYRTITDFREKLKHPVMSVSYKEVDRY
DAPGIALYPGQAQLLSCKHHYEVIPPLTSPGQPGDMNCTTQRINYTDPFS
NQTVKSALIVQGPREVKKRELVFLQFRLNKSSEDFSAIDYLLFSSFQEFL
QSPNRVGFMQACESAYSSWKFSGGFRTWVKMSLVKTKEEDGREAVEFRQE
TSVVNYIDQRPAAKKSAQLFFVVFEWKDPFIQKVQDIVTANPWNTIALLC
GAFLALFKAAEFAKLSIKWMIKIRKRYL
3D structure
PDB8fbl Inhibition of the proton-activated chloride channel PAC by PIP 2.
ChainB
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PIO B F92 R93 V100 L309 F31 R32 V39 L248
External links
PDB RCSB:8fbl, PDBe:8fbl, PDBj:8fbl
PDBsum8fbl
PubMed36633397
UniProtQ9H813|PACC1_HUMAN Proton-activated chloride channel (Gene Name=PACC1)

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