Structure of PDB 8f7v Chain B

Receptor sequence
>8f7vB (length=242) Species: 9606 (Homo sapiens) [Search protein sequence]
AAPSFDCGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGT
LISPEWVLTAAHCLEKSPRPSSYKVILGAHQEVPHVQEIEVSRLFLEPTR
KDIALLKLSSPAVITDKVIPACLPSPNYVVADRTECFITGWGETAGLLKE
AQLPVIENKVCNRYEFLNGRVQSTELCAGHLAGGTDSCQGDAGGPLVCFE
KDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTWIEGVMRNN
3D structure
PDB8f7v Synthesis and structural characterization of new macrocyclicplasmin inhibitors
ChainB
Resolution1.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.7: plasmin.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 EUA B G584 M585 G43 M44
BS02 EUA B H603 D646 R719 D735 S736 C737 Q738 T759 S760 W761 G762 G764 C765 H62 D102 R170 D186 S187 C188 Q189 T210 S211 W212 G213 G215 C216
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:8f7v, PDBe:8f7v, PDBj:8f7v
PDBsum8f7v
PubMed
UniProtP00747|PLMN_HUMAN Plasminogen (Gene Name=PLG)

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