Structure of PDB 8f5o Chain B

Receptor sequence
>8f5oB (length=1134) Species: 5689 (Leishmania tarentolae) [Search protein sequence]
MFVYLSKRIAMPNGVKVTSIAWNDGQGWLACGGEKGLLKVLKVDGGPQGQ
RSGGLSSSQTLEGHDTTVDLVTWNQQYCKLTSSDVSGRIIVWVLHKGMWF
EEMVNNRNSSRVVDFAWNPSGTKICITYEDGAVIVGGVDGNRYWGRELPY
KLAKVCWGADGNSILFGTATGEVYVHDASSGEHLSQVEIKCNDGKAPSPL
AGLSWHPAWVERPEPLATLAVCYQSGKLQLMTSIGDETPCNVDRDLPAHF
ISWNPSGTVLAVTAATPATEENGPGIVTQFFSTEGVHLRTLRVSGKQCGG
ITWEGGGLRVAIGVDSSVYFANVRPNYKYCYFKKTAVFAFTVPDKVEESV
MFWNVNTNERRTKSVRGLQYMNACKDACVLISRPDTTQQQRMIQLVNAIG
SPLETRFIDMELYTYDMNSSAVVCCGDESIYIWQFRDPSTAVDALDPISM
QASRAESQERVIHVCDLVRGDTAPTMKVRSALTNDLISAMCVSETHMFVS
LESGTLHVYQLSPLQLVSKYILFARAQSMSVNCNSTQLAVIHLGGITNVY
CIEREKFSLVPCKADTIDGVELKDVWNLRWAVDDPHRFAVMEKTRMLVYN
HGVAEEPVQSCANLCKFKSLKIRTLQLDELLLDPERPRKDYIVDFEAQLL
RDMRAVLRDGTAKEAYEFAESHNTKKLWELLAEHTLFQLDFTYAEVAFIH
CKDYAAIQFVKRVRSLDDPKKQLAEVNAYYRRFDEAERLYKDVDRKDLAL
DLRYRLGDWFGVVRLVQEGALLFQAWENIGDHYASRQKWSKAAQYYTQCR
HYRKLARIFYIIEDYEMLTQLISMGEHDKELMVTLGNMLLTVGLAEEAAK
AFIAANEPRMAVNGCVQVNMWNRAIALAKEHRLEDVGQLLEKYAKYLIHR
ERLTEAIELYRKAGKHDEAATLLAQLGKRAALRDALKAKKFYVLSALEVQ
KYRTTAIRTLDAAWRGAEAYHFLLMCQQQMADRNFKAALVLAMRLIEYDD
LVAPVDGYSLIALTAYLVKNFGLCSKAFARLEQAERNDEAPRPFADLARH
IFMTHSPVDTSVDSVPCPTCGSFNKEWAQRCIKCQQPFNTCIVSGCAIVS
EDGAWQCSVCHRKALEAVVDKYRNCPLCHTPRKG
3D structure
PDB8f5o Mechanism of IFT-A polymerization into trains for ciliary transport.
ChainB
Resolution3.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B C1214 C1217 C1232 C1107 C1110 C1125
BS02 ZN B C1174 C1188 C1191 C1067 C1081 C1084
Gene Ontology
Biological Process
GO:0042073 intraciliary transport
Cellular Component
GO:0005930 axoneme
GO:0031514 motile cilium
GO:0036064 ciliary basal body

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8f5o, PDBe:8f5o, PDBj:8f5o
PDBsum8f5o
PubMed36563665
UniProtA0A640KAU8

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