Structure of PDB 8es9 Chain B

Receptor sequence

>8es9B (length=287) Species: 9606 (Homo sapiens) [Search protein sequence]

VVSQHPSWVICKSGTSVKIECRSLDFQATTMFWYRQFPKQSLMLMATSNE
GSKATYEQGVEKDKFLINHASLTLSTLTVTSAHPEDSSFYICSAREWGGT
EAFFGQGTRLTVVEDLNKVFPPEVAVFEPSEAEISHTQKATLVCLATGFF
PDHVELSWWVNGKEVHSGVSTDPQPLKEQPALNDSRYCLSSRLRVSATFW
QNPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRADCGFTSVS
YQQGVLSATILYEILLGKATLYAVLVSALVLMAMVKR

3D structure

PDB

8es9 Structural analysis of cancer-relevant TCR-CD3 and peptide-MHC complexes by cryoEM

Chain

Resolution

3.25 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	B	W99 G101	W97 G99
BS02	Y01	B	S259 L263 L267	S257 L261 L265

External links

PDB	RCSB:8es9, PDBe:8es9, PDBj:8es9
PDBsum	8es9
PubMed	37100770

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