Structure of PDB 8es8 Chain B

Receptor sequence

>8es8B (length=287) Species: 9606 (Homo sapiens) [Search protein sequence]

KVTQSSRYLVKRTGEKVFLECVQDMDHENMFWYRQDPGLGLRLIYFSYDV
KMKEKGDIPEGYSVSREKKERFSLILESASTNQTSMYLCASSFTGPYNSP
LHFGNGTRLTVTEDLNKVFPPEVAVFEPSEAEISHTQKATLVCLATGFFP
DHVELSWWVNGKEVHSGVSTDPQPLKEQPALNDSRYCLSSRLRVSATFWQ
NPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRADCGFTSVSY
QQGVLSATILYEILLGKATLYAVLVSALVLMAMVKRK

3D structure

PDB

8es8 Structural analysis of cancer-relevant TCR-CD3 and peptide-MHC complexes by cryoEM

Chain

Resolution

2.65 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	B	F95 T96 Y99	F93 T94 Y97
BS02	Y01	B	S258 L266	S256 L264

External links

PDB	RCSB:8es8, PDBe:8es8, PDBj:8es8
PDBsum	8es8
PubMed	37100770

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