Structure of PDB 8ep7 Chain B

Receptor sequence
>8ep7B (length=323) Species: 261594 (Bacillus anthracis str. 'Ames Ancestor') [Search protein sequence]
MKTYYEQDANVGLLQGKTVAVIGYGSQGHAQAQNLRDSGVEVVVGVRPGK
SFEVAKADGFEVMSVSEAVRTAQVVQMLLPDEQQAHVYKAEVEENLREGQ
MLLFSHGFNIHFGQINPPSYVDVAMVAPKSPGHLVRRVFQEGVPALVAVH
QDATGTALHVALAYAKGVGCTRAGVIETTFQEETETDLFGEQAVLCGGVT
ALVKAGFETLTEGGYRPEIAYFECLHELKLIVDLMYEGGLTNMRHSISDT
AEFGDYVTGSRIVTDETKKEMKRVLTEIQQGEFAKKWILENQAGRPTYNA
MKKAEQNHQLEKVGEELREMMSW
3D structure
PDB8ep7 Crystal Structure of the Ketol-acid Reductoisomerase from Bacillus anthracis in the complex with NADP.
ChainB
Resolution2.2 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 1.1.1.86: ketol-acid reductoisomerase (NADP(+)).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAP B Y24 G25 S26 Q27 V46 R47 S51 L79 P80 D81 V87 H106 Y24 G25 S26 Q27 V46 R47 S51 L79 P80 D81 V87 H106
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004455 ketol-acid reductoisomerase activity
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0050661 NADP binding
Biological Process
GO:0008652 amino acid biosynthetic process
GO:0009082 branched-chain amino acid biosynthetic process
GO:0009097 isoleucine biosynthetic process
GO:0009099 L-valine biosynthetic process
Cellular Component
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8ep7, PDBe:8ep7, PDBj:8ep7
PDBsum8ep7
PubMed
UniProtQ81S27|ILVC2_BACAN Ketol-acid reductoisomerase (NADP(+)) 2 (Gene Name=ilvC2)

[Back to BioLiP]