Structure of PDB 8ejs Chain B

Receptor sequence
>8ejsB (length=283) Species: 9606 (Homo sapiens) [Search protein sequence]
LIYTAGGYFRQSLSYLEAYNPSDGTWLRLADLQVPRSGLAGCVVGGLLYA
VGGRNNSPDGNTDSSALDCYNPMTNQWSPCAPMSVPRNRIGVGVIDGHIY
AVGGSHGCIHHNSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVG
GFDGTNRLNSAECYYPERNEWRMITAMNTIRSGAGVCVLHNCIYAAGGYD
GQDQLNSVERYDVATATWTFVAPMKHRRSALGITVHQGRIYVLGGYDGHT
FLDSVECYDPDTDTWSEVTRMTSGRSGVGVAVT
3D structure
PDB8ejs The benefit of cyclization: a comparison of cyclic and linear peptide inhibitors of the KEAP1/Nrf2 protein-protein interaction
ChainB
Resolution2.82 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B Y334 S363 R380 N382 R415 R483 S508 G509 Y525 S555 Y572 F577 S602 Y8 S37 R54 N56 R89 R157 S182 G183 Y199 S229 Y246 F251 S276
External links
PDB RCSB:8ejs, PDBe:8ejs, PDBj:8ejs
PDBsum8ejs
PubMed
UniProtQ14145|KEAP1_HUMAN Kelch-like ECH-associated protein 1 (Gene Name=KEAP1)

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