Structure of PDB 8egn Chain B

Receptor sequence
>8egnB (length=299) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence]
HHHMRRIHFVGIGGAGMCGIAEVLLNLGYEVSGSDLKASAVTERLEKFGA
QIFIGHQAENADGADVLVVSSAINRANPEVASALERRIPVVPRAEMLAEL
MRYRHGIAVAGTHGKTTTTSLIASVFAAGGLDPTFVIGGRLNAAAQLGAS
RYLVAEADESDASFLHLQPMVAVVTNIDADDFNKLKKTFVEFLHNLPFYG
LAVMCVDDPVVREILPQIARPTVTYGLSEDADVRAINIRQEGMRTWFTVL
RPEREPLDVSVNMPGLHNVLNSLATIVIATDEGISDEAIVQGLSGFQGV
3D structure
PDB8egn Crystal Structure of UDP-N-acetylmuramate-L-alanine ligase (UDP-N-acetylmuramoyl-L-alanine synthetase, MurC) Pseudomonas aeruginosa in complex with ligand AZ-13643701
ChainB
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.3.2.8: UDP-N-acetylmuramate--L-alanine ligase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 WIR B H117 G118 T182 N183 C219 Y239 H281 L284 N285 H113 G114 T175 N176 C205 Y225 H267 L270 N271
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0008763 UDP-N-acetylmuramate-L-alanine ligase activity
GO:0016881 acid-amino acid ligase activity
Biological Process
GO:0009058 biosynthetic process

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:8egn, PDBe:8egn, PDBj:8egn
PDBsum8egn
PubMed
UniProtQ9HW02|MURC_PSEAE UDP-N-acetylmuramate--L-alanine ligase (Gene Name=murC)

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