Structure of PDB 8efv Chain B

Receptor sequence
>8efvB (length=314) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
EDLALRPKTLDEYIGQERLKQKLRVYLEAAKARKEPLEHLLLFGPPGLGK
TTLAHVIAHELGVNLRVTSGPAIPGDLAAILANSLEEGDILFIDEIHRLS
RQAEEHLYPAMEDFVMDIVIGQGPAARTIRLELPRFTLIGATTRPGLITA
PLLSRFGIVEHLEYYTPEELAQGVMRDARLLGVRITEEAALEIGRRSRGT
MRVAKRLFRRVRDFAQVAGEEVITRERALEALAALGLDELGLEKRDREIL
EVLILRFGGGPVGLATLATALSEDPGTLEEVHEPYLIRQGLLKRTPRGRV
ATELAYRHLGYPPP
3D structure
PDB8efv Structure of single homo-hexameric Holliday junction ATP-dependent DNA helicase RuvB motor
ChainB
Resolution2.97 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B R104 R147 R300 R101 R144 R297
BS02 dna B V265 T269 P299 R300 G301 R302 V262 T266 P296 R297 G298 R299
BS03 AGS B E115 R158 E112 R155
BS04 AGS B A5 L6 R7 P8 Y14 I15 G48 G50 K51 T52 T53 Y168 R205 A4 L5 R6 P7 Y13 I14 G47 G49 K50 T51 T52 Y165 R202
Gene Ontology
Molecular Function
GO:0000400 four-way junction DNA binding
GO:0003677 DNA binding
GO:0005524 ATP binding
GO:0009378 four-way junction helicase activity
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0006281 DNA repair
GO:0006310 DNA recombination
GO:0032508 DNA duplex unwinding
Cellular Component
GO:0005737 cytoplasm
GO:0048476 Holliday junction resolvase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8efv, PDBe:8efv, PDBj:8efv
PDBsum8efv
PubMed
UniProtQ5SL87|RUVB_THET8 Holliday junction branch migration complex subunit RuvB (Gene Name=ruvB)

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