Structure of PDB 8ea5 Chain B

Receptor sequence
>8ea5B (length=119) Species: 9606 (Homo sapiens) [Search protein sequence]
TESYCGPCPKNWICYKNNCYQFFDEEKNWYESQASCMSQNASLLKVYSKE
DQDLLKLVKSYHWMGLVHWQWEDGSSLSPNLLTIIEMQKGDCALYASSFK
GYIENCSTPNTYICMQRTV
3D structure
PDB8ea5 Identification of small-molecule protein-protein interaction inhibitors for NKG2D.
ChainB
Resolution1.63 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 VN8 B I104 F113 L145 L146 L148 V149 I13 F22 L54 L55 L57 V58
Gene Ontology
Biological Process
GO:0045954 positive regulation of natural killer cell mediated cytotoxicity

View graph for
Biological Process
External links
PDB RCSB:8ea5, PDBe:8ea5, PDBj:8ea5
PDBsum8ea5
PubMed37098070
UniProtP26718|NKG2D_HUMAN NKG2-D type II integral membrane protein (Gene Name=KLRK1)

[Back to BioLiP]