Structure of PDB 8ea3 Chain B

Receptor sequence

>8ea3B (length=257) Species: 34078 (Scytonema hofmannii) [Search protein sequence]

EWLQAEIARLKGKSIVPLQQVKTLHDWLDGKRKARKSCRVVGESRTGKTV
ACDAYRYRHKPQQEAGRPPTVPVVYIRPHQKCGPKDLFKKITEYLKYRVT
KGTVSDFRDRTIEVLKGCGVEMLIIDEADRLKPETFADVRDIAEDLGIAV
VLVGTDRLDAVIKRDEQVLERFRAHLRFGKLSGEDFKNTVEMWEQMVLKL
PVSSNLKSKEMLRILTSATEGYIGRLDEILREAAIRSLSRGLKKIDKAVL
QEVAKEY

3D structure

PDB

8ea3 Structures of the holo CRISPR RNA-guided transposon integration complex.

Chain

Resolution

3.7 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	dna	B	K119 R182	K101 R164
BS02	dna	B	T121 V122	T103 V104
BS03	peptide	B	K31 S32 I33 P35 D71 R74 Y75 P79 M214	K13 S14 I15 P17 D53 R56 Y57 P61 M196
BS04	ATP	B	V34 S62 G65 K66 T67 V68 W211 G242	V16 S44 G47 K48 T49 V50 W193 G224
BS05	ATP	B	Q185 R189	Q167 R171

External links

PDB	RCSB:8ea3, PDBe:8ea3, PDBj:8ea3
PDBsum	8ea3
PubMed	36442503
UniProt	A0A8J0PCL3

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