Structure of PDB 8e9b Chain B

Receptor sequence
>8e9bB (length=387) Species: 284812 (Schizosaccharomyces pombe 972h-) [Search protein sequence]
SAPIVLDNGTGFVKVGYAKDNFPRFQFPSIVGRPILRAEEKTGNVQIKDV
MVGDEAEAVRSLLQVKYPMENGIIRDFEEMNQLWDYTFFEKLKIDPRGRK
ILLTEPPMNPVANREKMCETMFERYGFGGVYVAIQAVLSLYAQGLSSGVV
VDSGDGVTHIVPVYESVVLNHLVGRLDVAGRDATRYLISLLLRKGYAFNR
TADFETVREMKEKLCYVSYDLELDHKLSEETTVLMRNYTLPDGRVIKVGS
ERYECPECLFQPHLVGSEQPGLSEFIFDTIQAADVDIRKYLYRAIVLSGG
SSMYAGLPSRLEKEIKQLWFERVLHGDPARLPNFKVKIEDAPRRRHAVFI
GGAVLADIMAQNDHMWVSKAEWEEYGVRALDKLGPRT
3D structure
PDB8e9b Mechanism of actin filament branch formation by Arp2/3 complex revealed by a high-resolution cryo-EM structureof the branch junction.
ChainB
Resolution3.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP B G11 T12 F14 K16 G156 D157 K213 E214 G302 M305 Y306 R347 G9 T10 F12 K14 G154 D155 K211 E212 G300 M303 Y304 R345
Gene Ontology
Molecular Function
GO:0003779 actin binding
GO:0005524 ATP binding
GO:0051015 actin filament binding
Biological Process
GO:0000147 actin cortical patch assembly
GO:0006897 endocytosis
GO:0034314 Arp2/3 complex-mediated actin nucleation
GO:0090135 actin filament branching
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005885 Arp2/3 protein complex
GO:0005938 cell cortex
GO:0030479 actin cortical patch
GO:0031097 medial cortex
GO:0051285 cell cortex of cell tip

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8e9b, PDBe:8e9b, PDBj:8e9b
PDBsum8e9b
PubMed36442092
UniProtQ9UUJ1|ARP2_SCHPO Actin-related protein 2 (Gene Name=arp2)

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