Structure of PDB 8e6o Chain B

Receptor sequence
>8e6oB (length=162) Species: 9606 (Homo sapiens) [Search protein sequence]
IIEFHVIGNSLANRRVLLWLVGLQNVFSHQLPRMPKEYIARLVFDPKHKT
LALIKDGRVIGGICFRMFPTQGFTEIVFCAVTSNEQVKGYGTHLMNHLKE
YHIKHNILYFLTYADEYAIGYFKKQGFSKDIKVPKSRYLGYIKDYEGATL
MECELNPRIPYT
3D structure
PDB8e6o Crystal structure of human GCN5 histone acetyltransferase domain
ChainB
Resolution2.37 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.-
2.3.1.48: histone acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 UQ3 B L531 F578 C579 A580 V581 Q586 V587 K588 G589 G591 T592 Y613 Y617 G620 Y621 K624 L31 F78 C79 A80 V81 Q86 V87 K88 G89 G91 T92 Y113 Y117 G120 Y121 K124
Gene Ontology
Molecular Function
GO:0004402 histone acetyltransferase activity
GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups

View graph for
Molecular Function
External links
PDB RCSB:8e6o, PDBe:8e6o, PDBj:8e6o
PDBsum8e6o
PubMed
UniProtQ92830|KAT2A_HUMAN Histone acetyltransferase KAT2A (Gene Name=KAT2A)

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