Structure of PDB 8e40 Chain B

Receptor sequence
>8e40B (length=118) Species: 11676 (Human immunodeficiency virus 1) [Search protein sequence]
RWQVMIVWQVDRMRINTWKRLVKHHMYISRKAKDWFYRHHYESTNPKISS
EVHIPLGDAKLVITTYWGLGQGVSIEWRKKRYSTQVDPDLADQLIHLHYF
DCKQIKPPLPSVRKLTED
3D structure
PDB8e40 Structural basis for HIV-1 antagonism of host APOBEC3G via Cullin E3 ligase.
ChainB
Resolution3.57 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna B R23 K26 Y30 I31 H42 H43 R20 K23 Y27 I28 H39 H40
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
Biological Process
GO:0019058 viral life cycle
Cellular Component
GO:0016020 membrane
GO:0020002 host cell plasma membrane
GO:0030430 host cell cytoplasm
GO:0044423 virion component

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8e40, PDBe:8e40, PDBj:8e40
PDBsum8e40
PubMed36598981
UniProtP12504|VIF_HV1N5 Virion infectivity factor (Gene Name=vif)

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