Structure of PDB 8e3i Chain B

Receptor sequence
>8e3iB (length=376) Species: 9606 (Homo sapiens) [Search protein sequence]
TFDGKRMRKAVNRKTIDYNPSVIKYLENRIWQRDQRDMRAIQPDAGYYND
LVPPIGMLNNPMNAVTTKFVRTSTNKVKCPVFVVRWTPEGRRLVTGASSG
EFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADHGGYVKYWQSN
MNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEERILR
GHGADVKCVDWHPTKGLVVSGSKDSQQPIKFWDPKTGQSLATLHAHKNTV
MEVKLNLNGNWLLTASRDHLCKLFDIRNLKEELQVFRGHKKEATAVAWHP
VHEGLFASGGSDGSLLFWHVGVEKEVGGMEMAHEGMIWSLAWHPLGHILC
SGSNDHTSKFWTRNRPGDKMRDRYNL
3D structure
PDB8e3i Molecular basis for the recognition of the AUUAAA polyadenylation signal by mPSF.
ChainB
Resolution2.53 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna B F43 D44 G45 R47 M48 R49 R54 K117 F153 I156 F2 D3 G4 R6 M7 R8 R13 K76 F112 I115
Gene Ontology
Biological Process
GO:0031124 mRNA 3'-end processing

View graph for
Biological Process
External links
PDB RCSB:8e3i, PDBe:8e3i, PDBj:8e3i
PDBsum8e3i
PubMed36130077
UniProtQ9C0J8|WDR33_HUMAN pre-mRNA 3' end processing protein WDR33 (Gene Name=WDR33)

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