Structure of PDB 8e2l Chain B

Receptor sequence
>8e2lB (length=461) Species: 8187 (Lates calcarifer) [Search protein sequence]
PEDEAQLIKTMFQITKVSNATLKKFGVRLFKPTKSLVFPWFAGPDSSLKG
LKLLSAQNTDTEKVTYNEATVPKISSYYNLFGLTLVGRMDSEVVLTGHEL
DTLAVSQATGLPSVALPRGVSCLPPMLLPYLEQFKRVTLWLGHDIRSWEA
SKIFSRKLGLRRCSLVRPGEDRPCPLEALARGKNLSRIIKTSIPAAHKSI
VSFKQLREDVYGELLNTEQVAGVKWTRFPELNRILKGHRKGELTVFTGPT
GSGKTTFISEVALDLCIQGVNTLWGSFQINNVRLAKIMLTQFAMQRLEEN
LEQYDFWADKFEELPLYFMTFHGQQNIKTVLDTMQHAVYLYDINHVIIDN
LQFMMGQIDKYAVQDHIIGAFRKFATNTSCHVTLIIHPRKEEDDRELQTA
SIFGSAKASQEADNVLILQEKKLVTCPGRRSLQVTKNRFDGDVGIFPLDF
IKSSLTFSAPI
3D structure
PDB8e2l Structural and dynamic basis of DNA capture and translocation by mitochondrial Twinkle helicase.
ChainB
Resolution3.51 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B Y412 K441 G455 Y361 K390 G404
BS02 ATP B K487 R489 K436 R438
BS03 ATP B G298 G300 K301 T302 T303 Q325 R481 F501 F508 G251 G253 K254 T255 T256 Q278 R430 F450 F457
BS04 MG B T302 Q325 T255 Q278
Gene Ontology
Molecular Function
GO:0003678 DNA helicase activity
GO:0003697 single-stranded DNA binding
GO:0005524 ATP binding
GO:0043139 5'-3' DNA helicase activity
Biological Process
GO:0006260 DNA replication

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Molecular Function
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Biological Process
External links
PDB RCSB:8e2l, PDBe:8e2l, PDBj:8e2l
PDBsum8e2l
PubMed36400570
UniProtA0A4W6C5C5

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