Structure of PDB 8e0p Chain B

Receptor sequence
>8e0pB (length=789) Species: 562,10090 [Search protein sequence]
GKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATG
DGPDIIFWAHDRFGGYAQSGLLAEITPAAAFQDKLYPFTWDAVRYNGKLI
AYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEP
YFTWPLIAADGGYAFKYAAGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHM
NADTDYSIAEHAFNHGETAMTINGPWAWSNIDTSAVNYGVTVLPTFKGQP
SKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVAL
KSYEEELVKDPRVAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGR
QTVDAALAAAQTNAAAFKESQCHHMLKHLHNGARITVQMPPTIEGHWVST
GCEVRSGPEFMTRSYRFYNNNTFKAYQFYYGSNRCTNPTYTLIIRGKIRL
RQASWIIRGGTEADYQLHGVQVICHTEAVAEQLSRLVNRTCPGFLAPGGP
WVQDVAYDLWQEESNHECTKAVNFAMHELQLIRVEKQYPHHSLDHLVEEL
FLGDIHTDATQRVFYRPSSYQPPLQNAKNHNHACIACRIIFRSDEHHPPI
LPPKADLTIGLHGEWVSQRCEVRPEVLFLTRHFIFHDNNNTWEGHYYHYS
DPVCKHPTFTIYARGRYSRGVLSSKVMGGTEFVFKVNHMKVTPMDAATAS
LLNVFSGNECGAEGSWQVGIQQDVTHTNGCVALGIKLPHTEYEIFKMEQD
TRGRYLLFNGQRPSDGSSPDRPEKRATSYQMPLVQCASS
3D structure
PDB8e0p Structure of WNT inhibitor adenomatosis polyposis coli down-regulated 1 (APCDD1), a cell-surface lipid-binding protein.
ChainB
Resolution2.33 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BGC B D17 K18 E114 Y158 D10 K11 E107 Y151
BS02 GLC B D68 R69 E156 P157 Y158 W343 D61 R62 E149 P150 Y151 W336
Gene Ontology
Molecular Function
GO:0015144 carbohydrate transmembrane transporter activity
GO:0017147 Wnt-protein binding
GO:0042802 identical protein binding
GO:1901982 maltose binding
Biological Process
GO:0001942 hair follicle development
GO:0008643 carbohydrate transport
GO:0015768 maltose transport
GO:0016055 Wnt signaling pathway
GO:0030178 negative regulation of Wnt signaling pathway
GO:0034219 carbohydrate transmembrane transport
GO:0042487 regulation of odontogenesis of dentin-containing tooth
GO:0042956 maltodextrin transmembrane transport
GO:0043615 astrocyte cell migration
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0030288 outer membrane-bounded periplasmic space
GO:0042597 periplasmic space
GO:0055052 ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8e0p, PDBe:8e0p, PDBj:8e0p
PDBsum8e0p
PubMed37155902
UniProtC3SHQ8;
Q3U128

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