Structure of PDB 8dnq Chain B

Receptor sequence
>8dnqB (length=116) Species: 9606 (Homo sapiens) [Search protein sequence]
PGRVTNQLQYLHKVVMKALWKHQFAWPFRQPVDAVKLGLPDYHKIIKQPM
DMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMAQTLEK
IFLQKVASMPQEEQEL
3D structure
PDB8dnq BRD2-BD1 in complex with cyclic peptide 2.2B
ChainB
Resolution1.84 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B W97 Q101 V103 K107 L108 N156 D160 D161 I162 M165 W26 Q30 V32 K36 L37 N85 D89 D90 I91 M94
External links
PDB RCSB:8dnq, PDBe:8dnq, PDBj:8dnq
PDBsum8dnq
PubMed37269828
UniProtP25440|BRD2_HUMAN Bromodomain-containing protein 2 (Gene Name=BRD2)

[Back to BioLiP]