Structure of PDB 8dl3 Chain B

Receptor sequence
>8dl3B (length=344) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHMDGLLNPRESSKFIAENSRDVFIDSGGVRRVAELLLAKAAGPELRVE
GWKALHELNPRAADEAAVNWVFVTDTLNFSFWSEQDEHKCVVRYRGKTYS
GYWSLCAAVNRALDEGIPITSASYYATVTLDQVRNILRSDTDVSMPLVEE
RHRILNETGKILLEKFGGSFLNCVRESENSAQKLMHLVVESFPSYRDVTL
FEGKRVSFYKRAQILVADTWSVLEGKGDGCFKDISSITMFADYRLPQVLA
HLGALKYSDDLLKKLLKGEMLSYGDRQEVEIRGCSLWCVELIRDCLLELI
EQKGEKPNGEINSILLDYYLWDYAHDHREDMKGIPFHRIRCIYY
3D structure
PDB8dl3 Structural basis of Qng1-mediated salvage of the micronutrient queuine from queuosine-5'-monophosphate as the biological substrate.
ChainB
Resolution2.26 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.2.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 QEI B W49 H53 N75 Y99 W100 I211 F237 D239 D314 Y315 W318 D319 W52 H56 N78 Y102 W103 I214 F240 D242 D317 Y318 W321 D322
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0005515 protein binding
GO:0016787 hydrolase activity
Biological Process
GO:0008150 biological_process
GO:0043174 nucleoside salvage
GO:0101030 tRNA-guanine transglycosylation
Cellular Component
GO:0005575 cellular_component

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8dl3, PDBe:8dl3, PDBj:8dl3
PDBsum8dl3
PubMed36610787
UniProtQ5T6V5|QNG1_HUMAN Queuosine 5'-phosphate N-glycosylase/hydrolase (Gene Name=QNG1)

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