Structure of PDB 8dir Chain B

Receptor sequence
>8dirB (length=215) Species: 9606 (Homo sapiens) [Search protein sequence]
APELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVD
GVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPA
PIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVE
WESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHE
ALHNHYTQKSLSLSP
3D structure
PDB8dir Fc gamma RI FG-loop functions as a pH sensitive switch for IgG binding and release.
ChainB
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 BMA B F241 F243 F11 F13
BS02 GAL B K246 E258 T260 K16 E28 T30
External links
PDB RCSB:8dir, PDBe:8dir, PDBj:8dir
PDBsum8dir
PubMed36814926
UniProtP01857|IGHG1_HUMAN Immunoglobulin heavy constant gamma 1 (Gene Name=IGHG1)

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