Structure of PDB 8daf Chain B

Receptor sequence
>8dafB (length=235) Species: 9606 (Homo sapiens) [Search protein sequence]
PNVPELILQLLQLEPDEDQVRARILGSLQEPTDQPAAFGLLCRMADQTFI
SIVDWARRCMVFKELEVADQMTLLQNCWSELLVFDHIYRQVQHGKEGSIL
LVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLALQLDRQEFVCLKFI
ILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHYPHSGDKFQQLLLCLV
EVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAK
3D structure
PDB8daf Comparison of activity, structure, and dynamics of SF-1 and LRH-1 complexed with small molecule modulators.
ChainB
Resolution2.59 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B R281 M295 E454 R57 M71 E230
BS02 IUW B C266 M268 T272 H310 V326 Q339 A340 C42 M44 T48 H86 V102 Q115 A116
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity

View graph for
Molecular Function
External links
PDB RCSB:8daf, PDBe:8daf, PDBj:8daf
PDBsum8daf
PubMed37328104
UniProtQ13285|STF1_HUMAN Steroidogenic factor 1 (Gene Name=NR5A1)

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