Structure of PDB 8d3h Chain B

Receptor sequence
>8d3hB (length=434) Species: 9606 (Homo sapiens) [Search protein sequence]
KAPSHVPFLLIGGGTAAFAAARSIRARDPGARVLIVSEDPELPYMRPPLS
KELWFSDDPNVTKTLRFKQKERSIYFQPPSFYVSAQDLPHIENGGVAVLT
GKKVVQLDVRDNMVKLNDGSQITYEKCLIATGGTPRSLSAIDRAGAEVKS
RTTLFRKIGDFRSLEKISREVKSITIIGGGFLGSELACALGRKARALGTE
VIQLFPEKGNMGKILPEYLSNWTMEKVRREGVKVMPNAIVQSVGVSSGKL
LIKLKDGRKVETDHIVAAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQA
RSNIWVAGDAACFYDIKLGRRRVEHHDHAVVSGRLAGENMTGAAKPYWHQ
SMFWSDLGPDVGYEAIGLVDSSLPTVGVFAGKGVIFYLRDKVVVGIVLWN
IFNRMPIARKIIKDGEQHEDLNEVAKLFNIHEVL
3D structure
PDB8d3h Integrating early structural selection into chemical library screening for drug discovery with high-throughput small-angle X-ray scattering (SAXS)
ChainB
Resolution2.51 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.6.99.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD B G138 G140 T141 A142 V162 E164 D165 R172 P173 K177 K232 V233 T260 F284 R285 G437 D438 E453 H454 H455 A458 W483 G12 G14 T15 A16 V36 E38 D39 R46 P47 K51 K103 V104 T131 F155 R156 G308 D309 E324 H325 H326 A329 W354
BS02 QBC B L311 E314 F482 W483 L182 E185 F353 W354
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0046983 protein dimerization activity

View graph for
Molecular Function
External links
PDB RCSB:8d3h, PDBe:8d3h, PDBj:8d3h
PDBsum8d3h
PubMed38671223
UniProtO95831|AIFM1_HUMAN Apoptosis-inducing factor 1, mitochondrial (Gene Name=AIFM1)

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