Structure of PDB 8d1f Chain B

Receptor sequence
>8d1fB (length=376) Species: 9606 (Homo sapiens) [Search protein sequence]
TVTYTARVANARFGGFSQLLLLWRGSIYKLLWRELLCFLGFYMALSAAYR
FVLTEGQKRYFEKLVIYCDQYASLIPVSFVLGFYVTLVVNRWWSQYLCMP
LPDALMCVVAGTVHGRDDRGRLYRRTLMRYAGLSAVLILRSVSTAVFKRF
PTIDHVVEAGFMTREERKKFENLNSSYNKYWVPCVWFSNLAAQARREGRI
RDNSALKLLLEELNVFRGKCGMLFHYDWISVPLVYTQVVTIALYSYFLAC
LIGRQFLDPAQGYKDHDLDLCVPIFTLLQFFFYAGWLKVAEQLINPFGED
DDDFETNFLIDRNFQVSMLAVDEMYDDLAVLEKDLYWDAAEARAPYTAAT
VFQLRQPSFQGSTFDITLAKEDMQFQ
3D structure
PDB8d1f Structures and gating mechanisms of human bestrophin anion channels.
ChainB
Resolution1.82 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA B Q293 N296 D301 D304 Q292 N295 D300 D303
Gene Ontology
Molecular Function
GO:0005254 chloride channel activity

View graph for
Molecular Function
External links
PDB RCSB:8d1f, PDBe:8d1f, PDBj:8d1f
PDBsum8d1f
PubMed35789156
UniProtQ8NFU1|BEST2_HUMAN Bestrophin-2a (Gene Name=BEST2)

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