Structure of PDB 8d0k Chain B

Receptor sequence
>8d0kB (length=362) Species: 9606 (Homo sapiens) [Search protein sequence]
RCEEETPSLLWGLDPVFLAFAKLYIRDILDMKESRQVPGVFLYNGHPIKQ
VDVLGTVIGVRERDAFYSYGVDDSTGVINCICWKKLNTESVSAAPSAARE
LSLTSQLKKLQETIEQKTKIEIGDTIRVRGSIRTYREEREIHATTYYKVD
DPVWNIQIARMLELPTIYRKVYDQPFHSSALEKEEALSNPGALDLPSLTS
LLSEKAKEFLMENRVQSFYQQELEMVESLLSLANQPVIHSASSDQVNFKK
DTTSKAIHSIFKNAIQLLQEKGLVFQKDDGFDNLYYVTREDKDLHRKIHR
IIQQDCQKPNHMEKGCHFLHILACARLSIRPGLSEAVLQQVLELLEDQSD
IVSTMEHYYTAF
3D structure
PDB8d0k Structures of the human CST-Pol alpha-primase complex bound to telomere templates.
ChainB
Resolution4.27 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B L24 R67 R69 W89 R139 Y141 R142 L18 R61 R63 W83 R133 Y135 R136
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003697 single-stranded DNA binding
GO:0005515 protein binding
GO:0042162 telomeric DNA binding
GO:0043047 single-stranded telomeric DNA binding
Biological Process
GO:0000723 telomere maintenance
GO:0010833 telomere maintenance via telomere lengthening
GO:0016233 telomere capping
GO:0032211 negative regulation of telomere maintenance via telomerase
GO:0045740 positive regulation of DNA replication
Cellular Component
GO:0000781 chromosome, telomeric region
GO:0001650 fibrillar center
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0043231 intracellular membrane-bounded organelle
GO:0045111 intermediate filament cytoskeleton
GO:1990879 CST complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8d0k, PDBe:8d0k, PDBj:8d0k
PDBsum8d0k
PubMed35830881
UniProtQ9H668|STN1_HUMAN CST complex subunit STN1 (Gene Name=STN1)

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