Structure of PDB 8cyf Chain B

Receptor sequence
>8cyfB (length=89) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
AVSFTLLQDQLQSVLDTLSEREAGVVRLRFGLTDGQPRTLDEIGQVYGVT
RERIRQIESKTMSKLRHPSRSQVLRDGTPEERLLRAIFG
3D structure
PDB8cyf Structural basis of DNA binding by the WhiB-like transcription factor WhiB3 in Mycobacterium tuberculosis.
ChainB
Resolution2.44 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B E501 R504 E52 R55
BS02 dna B R470 V498 T499 R502 Q505 R21 V49 T50 R53 Q56
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006352 DNA-templated transcription initiation
GO:0006355 regulation of DNA-templated transcription

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:8cyf, PDBe:8cyf, PDBj:8cyf
PDBsum8cyf
PubMed37142222
UniProtP9WGI1|SIGA_MYCTU RNA polymerase sigma factor SigA (Gene Name=sigA);
P9WGY9|RPOB_MYCTU DNA-directed RNA polymerase subunit beta (Gene Name=rpoB)

[Back to BioLiP]