Structure of PDB 8cv7 Chain B

Receptor sequence
>8cv7B (length=109) Species: 9606 (Homo sapiens) [Search protein sequence]
SSEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPMD
LSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDV
FEFRYAKMP
3D structure
PDB8cv7 Peptide 2.2E in complex with BRD2-BD2
ChainB
Resolution1.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B A367 W370 V376 L381 N429 H433 D434 V435 M438 A22 W25 V31 L36 N84 H88 D89 V90 M93
External links
PDB RCSB:8cv7, PDBe:8cv7, PDBj:8cv7
PDBsum8cv7
PubMed37269828
UniProtP25440|BRD2_HUMAN Bromodomain-containing protein 2 (Gene Name=BRD2)

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