Structure of PDB 8ct0 Chain B

Receptor sequence
>8ct0B (length=170) Species: 1894 (Kitasatospora aureofaciens) [Search protein sequence]
PLSLPLDLPGLVDGDTFLSIMGALPTGVTVVTTLGPDGEPYGLTCSAACS
VSKAPPLLLVCINRDSRVLKALLERGEFAVNVLRGGGESTSARFAAPVDD
RFRDVRWEPGSAGGVPVMSADVVAHAECRVAAALDAGDHTIVIGAVVAGG
PRPEVPSPLMYWRRSYARWP
3D structure
PDB8ct0 Crystal structures and complex formation of halogenase CtcP and FAD reductase CtcQ from the chlortetracycline biosynthetic pathway
ChainB
Resolution2.45 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.5.1.36: flavin reductase (NADH).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD B M26 N68 H144 Y166 R169 M21 N63 H139 Y161 R164
BS02 FAD B L48 T49 C50 S51 A52 C66 N68 S71 R72 A100 P102 V103 R106 L43 T44 C45 S46 A47 C61 N63 S66 R67 A95 P97 V98 R101
Gene Ontology
Molecular Function
GO:0010181 FMN binding
GO:0016491 oxidoreductase activity
GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
GO:0036382 flavin reductase (NADH) activity
GO:0042602 riboflavin reductase (NADPH) activity

View graph for
Molecular Function
External links
PDB RCSB:8ct0, PDBe:8ct0, PDBj:8ct0
PDBsum8ct0
PubMed
UniProtS4S3E3|CTCQ_KITAU Flavin reductase (NADH) (Gene Name=ctcQ)

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