Structure of PDB 8cqm Chain B

Receptor sequence
>8cqmB (length=230) Species: 1639 (Listeria monocytogenes) [Search protein sequence]
WDVNTHYWLFKQAEKILAKDVNHMRANLMNELKKFDKQIAQGIYDADHKN
PYYDTSTFLSHFYNPDRDNTYLPGFANAKITGAKYFNQSVTDYREGKFDT
AFYKLGLAIHYYTDISQPMHANNFTAISYPPGYHSAYENYVDTIKHNYQA
TEDMVAKRFSSDDVKDWLYENAKRAKADYPKIVNAKTKKSYLVGNSEWKK
DTVEPTGARLRDSQQTLAGFLEFWSKKTNE
3D structure
PDB8cqm Structural basis for the unique molecular properties of broad-range phospholipase C from Listeria monocytogenes.
ChainB
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.4.3: phospholipase C.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 FE B H128 H142 E146 H120 H134 E138
BS02 FE B W1 H14 D122 W1 H6 D114
Gene Ontology
Molecular Function
GO:0004629 phospholipase C activity
GO:0004767 sphingomyelin phosphodiesterase activity
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity
GO:0016788 hydrolase activity, acting on ester bonds
GO:0034480 phosphatidylcholine phospholipase C activity
GO:0046872 metal ion binding
Cellular Component
GO:0005576 extracellular region

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:8cqm, PDBe:8cqm, PDBj:8cqm
PDBsum8cqm
PubMed37838694
UniProtP33378|PHLC_LISMO Phospholipase C (Gene Name=plcB)

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