Structure of PDB 8cj2 Chain B

Receptor sequence
>8cj2B (length=154) Species: 9606 (Homo sapiens) [Search protein sequence]
MAKVQVNNVVVLDNPSPFYNPFQFEITFECIEDLSEDLEWKIIYVGSAES
EEYDQVLDSVLVGPVPAGRHMFVFQADAPNPGLIPDADAVGVTVVLITCT
YRGQEFIRVGYYVNNEYTETELRENPPVKPDFSKLQRNILASNPRVTRFH
INWE
3D structure
PDB8cj2 Unexpected binding modes of inhibitors to the histone chaperone ASF1 revealed by a foldamer scanning approach.
ChainB
Resolution2.127 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B V6 N7 N8 V9 V109 S142 P144 R145 V146 R148 V6 N7 N8 V9 V109 S142 P144 R145 V146 R148
BS02 peptide B A48 E51 D54 V94 G110 Y111 Y112 R145 A48 E51 D54 V94 G110 Y111 Y112 R145
Gene Ontology
Biological Process
GO:0006325 chromatin organization
Cellular Component
GO:0005634 nucleus

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Biological Process
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Cellular Component
External links
PDB RCSB:8cj2, PDBe:8cj2, PDBj:8cj2
PDBsum8cj2
PubMed37347155
UniProtQ9Y294|ASF1A_HUMAN Histone chaperone ASF1A (Gene Name=ASF1A)

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