Structure of PDB 8c76 Chain B

Receptor sequence
>8c76B (length=195) Species: 274 (Thermus thermophilus) [Search protein sequence]
DLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAW
HRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGA
MLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRA
LPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWL
3D structure
PDB8c76 Redox driven B 12 -ligand switch drives CarH photoresponse.
ChainB
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 B12 B L124 R125 G128 E129 W131 H132 E141 H177 S222 L225 G247 G248 Q249 M264 L267 L43 R44 G47 E48 W50 H51 E60 H96 S141 L144 G166 G167 Q168 M183 L186
Gene Ontology
Molecular Function
GO:0031419 cobalamin binding
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:8c76, PDBe:8c76, PDBj:8c76
PDBsum8c76
PubMed37604813
UniProtQ53W62|CARH_THET8 HTH-type transcriptional repressor CarH (Gene Name=carH)

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