Structure of PDB 8b9y Chain B

Receptor sequence
>8b9yB (length=316) Species: 5693 (Trypanosoma cruzi) [Search protein sequence]
FDPRNNVAPSMDALIGETPAVYLKRMNDTAATIVLKLECENPMASVKDRL
AYAIYDKAEKEGKIIPGKSVIVEATSGNTGIALAHIGTIRGYKVIIVMPE
SMSIERRCLMRIFGAEVILTPAALGMKGALEAVNRIVSNNPDAVSANQFA
TKYNAQIHEETTGPEIWRQTKGHVDCFVAGVGTGGTITGVARYLKSVGCG
ATIFAVEPAESPVLSGGKPGPHRIQGIGAGFVPEVFEAALVDEVIQVSGD
EAIDTAQKLPRTDGIFCGFSGGANVYAALQIAKRPEMAGKTIVTVIPSYG
ERYLSTALYVLSAADI
3D structure
PDB8b9y Cysteine synthase: multiple structures of a key enzyme in cysteine synthesis and a potential drug target for Chagas disease and leishmaniasis.
ChainB
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 RIB B E57 N58 P59 A61 E40 N41 P42 A44
BS02 PLP B K64 N95 G199 T200 G201 T203 G243 S287 P314 S315 K47 N78 G182 T183 G184 T186 G226 S270 P297 S298
Gene Ontology
Molecular Function
GO:0004124 cysteine synthase activity
Biological Process
GO:0006535 cysteine biosynthetic process from serine
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8b9y, PDBe:8b9y, PDBj:8b9y
PDBsum8b9y
PubMed37204818
UniProtQ4CST7

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