Structure of PDB 8b58 Chain B

Receptor sequence
>8b58B (length=200) Species: 5811 (Toxoplasma gondii) [Search protein sequence]
SSLLSESELPAGISYAEAMEGGSRPLLHPDNPVVFFDISIGSHEAGRIKI
ELFKNLAPKSAENFRQFCTGEFRQNQVPIGYKGATFHRIIKNFMIQGGDF
VKGDGTGRLSIYGSSFPDEAFVLPHFRSGLLSLANSGPDTNGCQFFITCA
KCDWLNRKHVVFGQVLGKESMQVVRKIEHVTVDGGNRPRIPVTVTQCGEL
3D structure
PDB8b58 Structural Basis for Cyclosporin Isoform-Specific Inhibition of Cyclophilins from Toxoplasma gondii .
ChainB
Resolution1.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.2.1.8: peptidylprolyl isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B R99 F104 Q107 G116 A145 N146 S147 Q155 F157 W165 H170 R88 F93 Q96 G105 A134 N135 S136 Q144 F146 W154 H159
Gene Ontology
Molecular Function
GO:0003755 peptidyl-prolyl cis-trans isomerase activity
Biological Process
GO:0000413 protein peptidyl-prolyl isomerization
GO:0006457 protein folding
Cellular Component
GO:0043231 intracellular membrane-bounded organelle

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8b58, PDBe:8b58, PDBj:8b58
PDBsum8b58
PubMed36653744
UniProtB9PS61

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