Structure of PDB 8aop Chain B

Receptor sequence
>8aopB (length=104) Species: 431944 (Magnetospirillum gryphiswaldense MSR-1) [Search protein sequence]
SIFRCRQCGQTISRRDWLLPMGGDHEHVVFNPAGMIFRVWCFSLAQGLRL
IGAPSGEFSWFKGYDWTIALCGQCGSHLGWHYEGGSQPQTFFGLIKDRLA
EGPA
3D structure
PDB8aop Synthesis of novel glutarimide ligands for the E3 ligase substrate receptor Cereblon (CRBN): Investigation of their binding mode and antiproliferative effects against myeloma cell lines.
ChainB
Resolution1.944 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B C24 C27 C90 C93 C5 C8 C71 C74
BS02 MW6 B N50 P51 F77 S78 W79 W85 W99 Y101 N31 P32 F58 S59 W60 W66 W80 Y82
Gene Ontology
Molecular Function
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:8aop, PDBe:8aop, PDBj:8aop
PDBsum8aop
PubMed36476642
UniProtA4TVL0

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