Structure of PDB 8ai2 Chain B

Receptor sequence

>8ai2B (length=323) Species: 1423 (Bacillus subtilis) [Search protein sequence]

LYFQGHMYNKTVSINLDSRCNASCDHCCFSSSPTSTTRMEKEYIRELVTE
FAKNKTIQVISFTGGEVFLDYKFLKELMEIIKPYEKQITLISNGFWGLSK
KKVQEYFHDMNSLNVIALTISYDEYHAPFVKSSSIKNILEHSRKYPDIDI
SLNMAVTKDKMSNHILEELGDSILGVKITKFPMISVGAAKTRIKQENIHK
FYSLEDEDSLHCPGYDIVYHHDGEIYPCCSPAIFETKITLREEYNQSFER
TVEKLNSNLLLFILRKEGFKWFLNILKENNKIEEFDIPYEFSSICGVCGS
LFNSAEKINYFYPYMEKYYNENF

3D structure

PDB

8ai2 Structural and mechanistic basis for RiPP epimerization by a radical SAM enzyme.

Chain

Resolution

2.393 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	peptide	B	S7 T57 I85 F175 I178 P207 G208 D210 C223 S224 P225 F228 C289	S13 T63 I91 F181 I184 P213 G214 D216 C229 S230 P231 F234 C295
BS02	SF4	B	C14 A16 C18 C21 S25 G59 N87 H120	C20 A22 C24 C27 S31 G65 N93 H126
BS03	SF4	B	C206 P207 C222 S224 F263 C289 C292	C212 P213 C228 S230 F269 C295 C298
BS04	SAH	B	H20 C22 G58 G59 I85 S115 H120 F175 I178	H26 C28 G64 G65 I91 S121 H126 F181 I184

Gene Ontology

	Molecular Function
GO:0003824	catalytic activity
GO:0046872	metal ion binding
GO:0051536	iron-sulfur cluster binding
GO:0051539	4 iron, 4 sulfur cluster binding

View graph for
Molecular Function

External links

PDB	RCSB:8ai2, PDBe:8ai2, PDBj:8ai2
PDBsum	8ai2
PubMed	38158457
UniProt	Q45595\|YYDG_BACSU Putative peptide biosynthesis protein YydG (Gene Name=yydG)

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