Structure of PDB 8afa Chain B

Receptor sequence
>8afaB (length=402) Species: 311400 (Thermococcus kodakarensis) [Search protein sequence]
WKILWGLVLGAVFGLIAGHFGYAGAVKTYIKPFGDLFVRLLKMLVMPIVL
ASLVVGAASISPARLGRVGVKIVVYYLATSAMAVFFGLIVGRLFNVGANV
PPSLVQTLLNIVPTNPFASLAKGEVLPVIFFAIILGIAITYLMNRNEERV
RKSAETLLRVFDGLAEAMYLIVGGVMQYARIGVFALIAYVMAEQGVRVVG
PLAKVVGAVYTGLFLQIVITYFILLKVFGIDPIKFIRKAKDAMITAFVTR
SSSGTLPVTMRVAEEEMGVDKGIFSFTLPLGATINMDGTALYQGVTVLFV
ANAIGHPLTLGQQLVVVLTAVLASIGTAGVPGAGAIMLAMVLQSVGLDLT
PGSPVALAYAMILGIDAILDMGRTMVNVTGDLAGTVIVAKTEKELDESKW
IS
3D structure
PDB8afa Mutation in glutamate transporter homologue GltTk provides insights into pathologic mechanism of episodic ataxia 6.
ChainB
Resolution3.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ASP B S279 S280 T317 G357 V358 A361 G362 D398 R401 T402 S251 S252 T289 G329 V330 A333 G334 D370 R373 T374
Gene Ontology
Molecular Function
GO:0015293 symporter activity
Biological Process
GO:0046942 carboxylic acid transport
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane

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Cellular Component
External links
PDB RCSB:8afa, PDBe:8afa, PDBj:8afa
PDBsum8afa
PubMed37002226
UniProtQ5JID0

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