Structure of PDB 8act Chain B

Receptor sequence
>8actB (length=857) Species: 9606 (Homo sapiens) [Search protein sequence]
DSEMAVFGAAAPYLRKSEKERLEAQTRPFDLKKDVFVPDDKQEFVKAKIV
SREGGKVTAETEYGKTVTVKEDQVMQQNPPKFDKIEDMAMLTFLHEPAVL
YNLKDRYGSWMIYTYSGLFCVTVNPYKWLPVYTPEVVAAYRGKKRSEAPP
HIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVILEDQ
IIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLE
KSRVIFQLKAERDYHIFYQILSNKKPELLDMLLITNNPYDYAFISQGETT
VASIDDAEELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKLKQE
QAEPDGTEEADKSAYLMGLNSADLLKGLCHPRVKVYVTKGQNVQQVIYAT
GALAKAVYERMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFE
QLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLI
EKPMGIMSILEEECMFPKATDMTFKAKLFDNHLGKSANFQKPRNIKGKPE
AHFSLIHYAGIVDYNIIGWLQKNKDPLNETVVGLYQKSSLKLLSTLFANY
AGFQTVSALHRENLNKLMTNLRSTHPHFVRCIIPNETKSPGVMDNPLVMH
QLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAIPEGQFIDSRKG
AEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQAQ
SRGVLARMEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYFKIKPLLK
SAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQV
QAEQDNL
3D structure
PDB8act Cryo-EM structure of the folded-back state of human beta-cardiac myosin.
ChainB
Resolution3.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP B N126 P127 X129 W130 Y134 G181 G183 K184 T185 V186 N238 N240 N124 P125 X127 W128 Y132 G179 G181 K182 T183 V184 N219 N221
BS02 MG B T185 S242 T183 S223
Gene Ontology
Molecular Function
GO:0003774 cytoskeletal motor activity
GO:0005524 ATP binding
GO:0051015 actin filament binding
Cellular Component
GO:0016459 myosin complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:8act, PDBe:8act, PDBj:8act
PDBsum8act
PubMed37258552
UniProtP12883|MYH7_HUMAN Myosin-7 (Gene Name=MYH7)

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