Structure of PDB 8aap Chain B

Receptor sequence
>8aapB (length=162) Species: 9606 (Homo sapiens) [Search protein sequence]
DPREVILCKDQDGKIGLRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQ
INGENCAGWSSDKAHKVLKQAFGEKITMTIRDRPFERTITMHKDSTGHVG
FIFKNGKITSIVKDSSAARNGLLTEHNICEINGQNVIGLKDSQIADILST
SGTVVTITIMPA
3D structure
PDB8aap Discovery of a PDZ Domain Inhibitor Targeting the Syndecan/Syntenin Protein-Protein Interaction: A Semi-Automated "Hit Identification-to-Optimization" Approach.
ChainB
Resolution2.174 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 LLV B D204 H208 V209 G210 F211 I212 F213 V222 D251 S252 D94 H98 V99 G100 F101 I102 F103 V112 D141 S142
External links
PDB RCSB:8aap, PDBe:8aap, PDBj:8aap
PDBsum8aap
PubMed36939673
UniProtO00560|SDCB1_HUMAN Syntenin-1 (Gene Name=SDCBP)

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