Structure of PDB 8aak Chain B

Receptor sequence

>8aakB (length=165) Species: 9606 (Homo sapiens) [Search protein sequence]

AMDPREVILCKDQDGKIGLRLKSIDNGIFVQLVQANSPASLVGLRFGDQV
LQINGENCAGWSSDKAHKVLKQAFGEKITMTIRDRPFERTITMHKDSTGH
VGFIFKNGKITSIVKDSSAARNGLLTEHNICEINGQNVIGLKDSQIADIL
STSGTVVTITIMPAF

3D structure

PDB

8aak Discovery of a PDZ Domain Inhibitor Targeting the Syndecan/Syntenin Protein-Protein Interaction: A Semi-Automated "Hit Identification-to-Optimization" Approach.

Chain

Resolution

2.554 Å

3D
structure

[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	LL6	B	H208 V209 G210 F211 I212 F213 V222	H100 V101 G102 F103 I104 F105 V114

External links

PDB	RCSB:8aak, PDBe:8aak, PDBj:8aak
PDBsum	8aak
PubMed	36939673
UniProt	O00560\|SDCB1_HUMAN Syntenin-1 (Gene Name=SDCBP)

[Back to BioLiP]