Structure of PDB 8a74 Chain B

Receptor sequence
>8a74B (length=319) Species: 80249 (Phaedon cochleariae) [Search protein sequence]
SKEESREFMAIFPDIVRDLTDATDIPEVTKRFAKVLQYNVPTGKKTRGLS
TVIAYKMLEKPENLTPENVRLAGILGWCVELLQASLLIMDDLMDRSETRR
LAINDCLHVESSLYSVLRKYFSHLPCYVPIIELFHDVNFKTNMGQSLDAL
CMKDGRPILSQFTMKRYSSIVKYKTSYYTFQLPVSLGMYLADMYDPEQHR
QAKTILMEIGEFAQIQDDFLDAFGDVGTDIKEGKCSWLAVVALQRSNPAQ
RQIMEEHYGRPEPESTQIIKNLYIELGLPATFAVYEEESFNIIRTHIHQI
SKGLPHDLFFKIMKKIYKR
3D structure
PDB8a74 Metal-dependent enzyme symmetry guides the biosynthetic flux of terpene precursors.
ChainB
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.5.1.1: dimethylallyltranstransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG B D179 D183 D90 D94
BS02 MG B D179 D183 D90 D94
BS03 GPP B L175 D179 R188 T243 Q247 K276 Y280 K342 L86 D90 R99 T141 Q145 K174 Y178 K234
Gene Ontology
Molecular Function
GO:0004659 prenyltransferase activity
GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups
Biological Process
GO:0008299 isoprenoid biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:8a74, PDBe:8a74, PDBj:8a74
PDBsum8a74
PubMed37308711
UniProtM1JS91

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