Structure of PDB 8a4a Chain B

Receptor sequence
>8a4aB (length=172) Species: 9913 (Bos taurus) [Search protein sequence]
NFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFKN
EKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWS
TQIKTYSWDNAQVILVGNKCDMEDERVISTERGQHLGEQLGFEFFETSAK
DNINVKQTFERLVDIICDKMSE
3D structure
PDB8a4a Rep15 interacts with several Rab GTPases and has a distinct fold for a Rab effector.
ChainB
Resolution2.52 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GNP B S39 S40 G42 K43 T44 S45 S57 F59 S61 T62 G88 N143 K144 D146 M147 S173 A174 K175 S14 S15 G17 K18 T19 S20 S32 F34 S36 T37 G63 N118 K119 D121 M122 S148 A149 K150
BS02 MG B T44 T62 T19 T37
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0031489 myosin V binding
Biological Process
GO:0006887 exocytosis
GO:0009306 protein secretion
GO:0015031 protein transport
Cellular Component
GO:0005768 endosome
GO:0005886 plasma membrane
GO:0008021 synaptic vesicle

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Biological Process
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Cellular Component
External links
PDB RCSB:8a4a, PDBe:8a4a, PDBj:8a4a
PDBsum8a4a
PubMed35871249
UniProtP10949|RAB3C_BOVIN Ras-related protein Rab-3C (Gene Name=RAB3C)

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